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Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard <t>antimalarial</t> drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.
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Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard <t>antimalarial</t> drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.
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Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard <t>antimalarial</t> drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.
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Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard <t>antimalarial</t> drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.
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Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard <t>antimalarial</t> drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.
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Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard <t>antimalarial</t> drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.
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Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard antimalarial drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.

Journal: Scientific Reports

Article Title: Gossypol is a natural product with good antimalarial activity against Plasmodium falciparum clinical isolates

doi: 10.1038/s41598-025-85643-6

Figure Lengend Snippet: Dose-response curves for the Dd2_3.5 µM parasites, Dd2 parental strain and 3D7 parental strains of P. falciparum against standard antimalarial drugs. ( A ) Dose-response curves showing the response of chloroquine against Dd2_3.5 µM and Dd2 parental strain; ( B ) Dose-response curves showing the response of dihydroartemisinin (DHA) against Dd2_3.5 µM and Dd2 parental strain and ( C ) Dose-response curves showing the response of DHA and chloroquine against 3D7. Each data point represents the mean ± SEM ( n = 2). The plot shows the percentage parasitemia against the log of the concentration of the compound.

Article Snippet: To accelerate the development of new chemotherapeutic agents for the treatment of drug-resistant malaria parasites, institutions such as Medicines for Malaria Venture (MMV) are collaborating with GlaxoSmithKline and St. Jude Children’s Research Hospital to promote research and the rapid development of new antimalarial agents (malaria or pathogen box) .

Techniques: Concentration Assay

Summary of antimalarial drug resistance and the associated genes in laboratory P. falciparum strains. Adapted and modified from a previous study <xref ref-type= 53 ." width="100%" height="100%">

Journal: Scientific Reports

Article Title: Gossypol is a natural product with good antimalarial activity against Plasmodium falciparum clinical isolates

doi: 10.1038/s41598-025-85643-6

Figure Lengend Snippet: Summary of antimalarial drug resistance and the associated genes in laboratory P. falciparum strains. Adapted and modified from a previous study 53 .

Article Snippet: To accelerate the development of new chemotherapeutic agents for the treatment of drug-resistant malaria parasites, institutions such as Medicines for Malaria Venture (MMV) are collaborating with GlaxoSmithKline and St. Jude Children’s Research Hospital to promote research and the rapid development of new antimalarial agents (malaria or pathogen box) .

Techniques: Modification